1. Cancer Research UK Drug-DNA Interactions Research Group, Department of Oncology, Royal Free & University College Medical School, UCL, 91 Riding House Street, London W1W 7BS, U.K., Cancer Research UK Gene Targeted Drug Design Research Group, The School of Pharmacy, University of London, 29/39 Brunswick Square, London WC1N 1AX, U.K., and Yorkshire Cancer Research Laboratory of Drug Design, Tom Connors Cancer Research Centre, University of Bradford, All Saints Road, Bradford, West Yorkshire BD7 1DP, U.K.