Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs-Reference-Cited by-同舟云学术

Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs

Published:2008-01-25 Issue:4 Volume:51 Page:932-936
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gynther Mikko¹,Laine Krista¹,Ropponen Jarmo¹,Leppänen Jukka¹,Mannila Anne¹,Nevalainen Tapio¹,Savolainen Jouko¹,Järvinen Tomi¹,Rautio Jarkko¹

Affiliation:

1. Department of Pharmaceutical Chemistry, University of Kuopio, P.O. Box 1627, FI-70211 Kuopio, Finland, and Fennopharma Ltd., Microkatu 1, FI-70210 Kuopio, Finland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701175d

Reference31 articles.

1. BLOOD-BRAIN BARRIER DRUG TARGETING: THE FUTURE OF BRAIN DRUG DEVELOPMENT

2. THE CELL BIOLOGY OF THE BLOOD-BRAIN BARRIER

3. Prodrugs for improved CNS delivery

4. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

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