1. Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Fukuoka 812-8581, Japan; Department of Biochemical Engineering and Science, Kyushu Institute of Technology, Iizuka 820-8502, Japan; Departments of Etiology and Pathophysiology, and Pharmacology, National Cardiovascular Center Research Institute, Fujishirodai, Suita, Osaka 565-8565, Japan