Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA-Reference-Cited by-同舟云学术

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Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA

Published:2012-09-20 Issue:10 Volume:25 Page:2236-2252
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Shamovsky Igor¹,Ripa Lena¹,Blomberg Niklas¹,Eriksson Leif A.²,Hansen Peter¹,Mee Christine³,Tyrchan Christian⁴,O'Donovan Mike³,Sjö Peter¹

Affiliation:

1. Department of Medicinal Chemistry, R&I iMed, AstraZeneca R&D, Pepparedsleden 1, S-431 83 Mölndal, Sweden

2. Department of Chemistry and Molecular Biology, University of Gothenburg, S-412 96 Göteborg, Sweden

3. Genetic Toxicology, AstraZeneca R&D, Alderley Park, Macclesfield, Cheshire, SK10 4TG, United Kingdom

4. Department of Medicinal Chemistry, CVGI iMed, AstraZeneca R&D, Pepparedsleden 1, S-431 83 Mölndal, Sweden

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx300313b

Reference137 articles.

1. Aromatic Amines and Heterocyclic Aromatic Amines: From Tobacco Smoke to Food Mutagens

2. Organ Specificity of the Bladder Carcinogen 4-Aminobiphenyl in Inducing DNA Damage and Mutation in Mice

3. Avoided and avoidable risks of cancer

4. Structure−Activity Relationship Studies of Chemical Mutagens and Carcinogens: Mechanistic Investigations and Prediction Approaches

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