Completely N1-Selective Palladium-Catalyzed Arylation of Unsymmetric Imidazoles: Application to the Synthesis of Nilotinib
Author:
Affiliation:
1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja2102373
Reference74 articles.
1. Nilotinib in Imatinib-Resistant CML and Philadelphia Chromosome–Positive ALL
2. AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL
3. aKimura, T.; Kawano, K.; Doi, E.; Kitazawa, N.; Takaishi, M.; Ito, K.; Kaneko, T.; Sasaki, T.; Miyagawa, T.; Hagiwara, H.; Yoshida, Y.US20070117839, 2006.
4. The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators
5. Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: A comparison with diazepam and buspirone
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