Kinetic and Structural Characterization of Dihydrofolate Reductase from Streptococcus pneumoniae-Reference-Cited by-同舟云学术

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Kinetic and Structural Characterization of Dihydrofolate Reductase from Streptococcus pneumoniae

Published:2009-12-11 Issue:1 Volume:49 Page:195-206
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Lee Jeeyeon¹,Yennawar Neela H.²,Gam Jongsik¹,Benkovic Stephen J.¹

Affiliation:

1. Department of Chemistry, 414 Wartik Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802

2. Huck Institutes of the Life Sciences, 8B Althouse Lab, The Pennsylvania State University, University Park, Pennsylvania 16802

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi901614m

Reference34 articles.

1. Dihydrofolate reductase inhibitors as antibacterial agents

2. A Conservative Amino Acid Mutation in the Chromosome‐Encoded Dihydrofolate Reductase Confers Trimethoprim Resistance inStreptococcus pneumoniae

3. Molecular characterisation of Canadian paediatric multidrug-resistant Streptococcus pneumoniae from 1998–2004

4. In vitro activity of the novel diaminopyrimidine, iclaprim, in combination with folate inhibitors and other antimicrobials with different mechanisms of action

5. Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance

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2. Crystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate;PLOS Neglected Tropical Diseases;2023-04-27

3. Temperature-Dependent Kinetic Isotope Effects in R67 Dihydrofolate Reductase from Path-Integral Simulations;The Journal of Physical Chemistry B;2021-02-01

4. Mechanism of selectivity reveals novel antifolate drug interactions;2020-09-19

5. Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones;Cell Chemical Biology;2020-05

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