Hybrid Molecule from O2-(2,4-Dinitrophenyl)diazeniumdiolate and Oleanolic Acid: A Glutathione S-Transferase π-Activated Nitric Oxide Prodrug with Selective Anti-Human Hepatocellular Carcinoma Activity and Improved Stability-Reference-Cited by-同舟云学术

Hybrid Molecule from O2-(2,4-Dinitrophenyl)diazeniumdiolate and Oleanolic Acid: A Glutathione S-Transferase π-Activated Nitric Oxide Prodrug with Selective Anti-Human Hepatocellular Carcinoma Activity and Improved Stability

Published:2013-05-16 Issue:11 Volume:56 Page:4641-4655
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fu Junjie¹²,Liu Ling¹³,Huang Zhangjian¹²,Lai Yisheng¹²,Ji Hui¹,Peng Sixun¹²,Tian Jide⁴,Zhang Yihua¹²

Affiliation:

1. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China

2. Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, PR China

3. Department of Pharmacology, Medical College, Henan University of Science and Technology, Luoyang 471003, PR China

4. Department of Molecular and Medical Pharmacology, University of California, Los Angeles, California 90095, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400393u

Reference35 articles.

1. Current molecular design of intelligent drugs and imaging probes targeting tumor-specific microenvironments

2. Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases

3. Glutathione and related enzymes in multidrug resistance

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