Unconventional Origin of Metal Ion Rescue in the Hammerhead Ribozyme Reaction: Mn2+-Assisted Redox Conversion of 2‘-Mercaptocytidine to Cytidine-Reference-Cited by-同舟云学术

Unconventional Origin of Metal Ion Rescue in the Hammerhead Ribozyme Reaction: Mn2+-Assisted Redox Conversion of 2‘-Mercaptocytidine to Cytidine

Published:2000-11-21 Issue:49 Volume:122 Page:12069-12078
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Hamm Michelle L.¹,Nikolic Dejan¹,van Breemen Richard B.¹,Piccirilli Joseph A.¹

Affiliation:

1. Contribution from the Howard Hughes Medical Institute, The University of Chicago, Departments of Biochemistry and Molecular Biology, and Chemistry, 5841 South Maryland Avenue MC1028, Chicago, Illinois 60637, University of Illinois at Chicago, College of Pharmacy, Department of Medicinal Chemistry and Pharmacognosy, 833 South Wood Street, Chicago, Illinois 60612-7231

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja000379p

Reference43 articles.

1. The U5 and U6 Small Nuclear RNAs as Active Site Components of the Spliceosome

2. Metal ion catalysis in the Tetrahymena ribozyme reaction

3. Metal ion catalysis during splicing of premessenger RNA

4. A second catalytic metal ion in a group I ribozyme

5. Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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