Oxidative Deboronation of the Peptide Boronic Acid Proteasome Inhibitor Bortezomib: Contributions from Reactive Oxygen Species in This Novel Cytochrome P450 Reaction-Reference-Cited by-同舟云学术

Oxidative Deboronation of the Peptide Boronic Acid Proteasome Inhibitor Bortezomib: Contributions from Reactive Oxygen Species in This Novel Cytochrome P450 Reaction

Published:2006-03-25 Issue:4 Volume:19 Page:539-546
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Labutti Jason¹,Parsons Ian¹,Huang Ron¹,Miwa Gerald¹,Gan Liang-Shang¹,Daniels J. Scott¹

Affiliation:

1. Department of Drug Metabolism and Pharmacokinetics, Drug Safety and Disposition, and Department of Analytical Development, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts 02139

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx050313d

Reference30 articles.

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2. RELATIVE CONTRIBUTIONS OF THE FIVE MAJOR HUMAN CYTOCHROMES P450, 1A2, 2C9, 2C19, 2D6, AND 3A4, TO THE HEPATIC METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB

3. Coon, M. J., Vaz, A. D. N., McGinnity, D. F., and Peng, H.M. (1998) Multiple activated oxygen species in P450 catalysis: contributions to specificity in drug metabolism.Drug Metab. Dispos. 26, 1190−1193.

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