Analysis of Chemical Shift Changes Reveals the Binding Modes of Isoindolinone Inhibitors of the MDM2-p53 Interaction-Reference-Cited by-同舟云学术

Analysis of Chemical Shift Changes Reveals the Binding Modes of Isoindolinone Inhibitors of the MDM2-p53 Interaction

Published:2008-10-30 Issue:47 Volume:130 Page:16038-16044
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Riedinger Christiane¹,Endicott Jane A.¹,Kemp Stuart J.¹,Smyth Lynette A.¹,Watson Anna¹,Valeur Eric¹,Golding Bernard T.¹,Griffin Roger J.¹,Hardcastle Ian R.¹,Noble Martin E.¹,McDonnell James M.¹

Affiliation:

1. Laboratory of Molecular Biophysics, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, U.K., and Northern Institute for Cancer Research, Bedson Building, University of Newcastle, NE1 4RW, U.K.

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja8062088

Reference29 articles.

1. p53, the Cellular Gatekeeper for Growth and Division

2. p53 and Human Cancer: The First Ten Thousand Mutations

3. The MDM2 gene amplification database

4. What the papers say: The p53-mdm2 autoregulatory feedback loop: A paradigm for the regulation of growth control by p53?

5. The p53-mdm-2 autoregulatory feedback loop.

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