A Novel Approach for a Water-Soluble Long-Acting Insulin Prodrug: Design, Preparation, and Analysis of [(2-Sulfo)-9-fluorenylmethoxycarbonyl]3-insulin
Author:
Affiliation:
1. Departments of Biological Chemistry and Organic Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm990533m
Reference25 articles.
1. Pharmacokinetic Considerations of New Insulin Formulations and Routes of Administration
2. Improving Insulin Therapy: Achievements and Challenges
3. Soluble, prolonged-acting insulin derivatives. III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30
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