14-Aminocamptothecins: Their Synthesis, Preclinical Activity, and Potential Use for Cancer Treatment-Reference-Cited by-同舟云学术

14-Aminocamptothecins: Their Synthesis, Preclinical Activity, and Potential Use for Cancer Treatment

Published:2011-02-22 Issue:6 Volume:54 Page:1715-1723
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Duan Jian-Xin¹,Cai Xiaohong¹,Meng Fanying¹,Sun Jessica D.¹,Liu Qian¹,Jung Donald¹,Jiao Hailong¹,Matteucci Jackson¹,Jung Brian¹,Bhupathi Deepthi¹,Ahluwalia Dharmendra¹,Huang Heli¹,Hart Charles P.¹,Matteucci Mark¹

Affiliation:

1. Threshold Pharmaceuticals, 1300 Seaport Blvd, Suite 500, Redwood City, California 94063, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101354u

Reference30 articles.

1. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

2. DNA TOPOISOMERASES

3. Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

4. Phase I Study of Weekly Intravenous Infusions of CPT-11, a New Derivative of Camptothecin, in the Treatment of Advanced Non-Small-Cell Lung Cancer

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