Polymerization Past the N2-Isopropylguanine and the N6-Isopropyladenine DNA Lesions with the Translesion Synthesis DNA Polymerases η and ι and the Replicative DNA Polymerase α
Author:
Affiliation:
1. Department of Biochemistry, Wake Forest University Health Sciences, Winston-Salem, North Carolina 27157, and Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx050114u
Reference67 articles.
1. Alekseyev, Y. O., and Romano, L. J. (2000) In vitro replication of primer-templates containing benzo [a] pyrene adducts by exonuclease-deficientEscherichia coliDNA polymerase I (Klenow fragment): effect of sequence context on lesion bypass.Biochemistry39,10431−10438.
2. Shibutani, S., Margulis, L. A., Geacintov, N. E., and Grollman, A. P. (1993) Translesional synthesis on a DNA-template containing a single stereoisomer of DG-(+)anti-BPDE or DG-(−)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo [a] pyrene).Biochemistry32,7531−7541.
3. Alekseyev, Y. O., Dzantiev, L., and Romano, L. J. (2001) Effects of benzo [a] pyrene DNA adducts onEscherichia coliDNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation.Biochemistry40,2282−2290.
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