Δ9-Tetrahydrocannabinol Disrupts Estrogen-Signaling through Up-Regulation of Estrogen Receptor β (ERβ)-Reference-Cited by-同舟云学术

Δ9-Tetrahydrocannabinol Disrupts Estrogen-Signaling through Up-Regulation of Estrogen Receptor β (ERβ)

Published:2013-06-11 Issue:7 Volume:26 Page:1073-1079
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Takeda Shuso¹,Yoshida Kazutaka¹,Nishimura Hajime¹,Harada Mari¹,Okajima Shunsuke¹,Miyoshi Hiroko¹,Okamoto Yoshiko¹,Amamoto Toshiaki²,Watanabe Kazuhito³,Omiecinski Curtis J.⁴,Aramaki Hironori¹

Affiliation:

1. Department of Molecular Biology, Daiichi University of Pharmacy, 22-1 Tamagawa-cho, Minami-ku, Fukuoka 815-8511, Japan

2. NEUES Corporation, Yaesu Center Building 3F, 1-6-6 Yaesu, Chuo-ku, Tokyo 103-0028, Japan

3. Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan

4. Center for Molecular Toxicology and Carcinogenesis, 101 Life Sciences Building, Pennsylvania State University, University Park, Pennsylvania 16802, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx4000446

Reference29 articles.

1. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1and CB2

2. The endocannabinoid system and cancer: therapeutic implication

3. Δ9-Tetrahydrocannabinol and Its Major Metabolite Δ9-Tetrahydrocannabinol-11-oic Acid as 15-Lipoxygenase Inhibitors

4. Induction of the fatty acid 2-hydroxylase (FA2H) gene by Δ⁹-tetrahydrocannabinol in human breast cancer cells

5. Failure of cannabinoid compounds to stimulate estrogen receptors

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