Recent Progress on the Identification of Metabotropic Glutamate 4 Receptor Ligands and Their Potential Utility as CNS Therapeutics-Reference-Cited by-同舟云学术

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Recent Progress on the Identification of Metabotropic Glutamate 4 Receptor Ligands and Their Potential Utility as CNS Therapeutics

Published:2011-07-18 Issue:8 Volume:2 Page:433-449
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Robichaud Albert J.¹,Engers Darren W.²,Lindsley Craig W.³²,Hopkins Corey R.³²

Affiliation:

1. Chemical & Pharmacokinetic Sciences, Lundbeck Research USA, 215 College Road, Paramus, New Jersey 07652, United States

2. Vanderbilt Specialized Chemistry Center for Accelerated Probe Development (MLPCN), Nashville, Tennessee 37232, United States

3. Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37232, United States

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/cn200043e

Reference82 articles.

1. Metabotropic glutamate receptors

2. Allosteric modulation of metabotropic glutamate receptors: Structural insights and therapeutic potential

3. Potential Psychiatric Applications of Metabotropic Glutamate Receptor Agonists and Antagonists

4. Recent developments in metabotropic glutamate receptors as novel drug targets

5. Glutamate Receptors

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3. New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties;Journal of Enzyme Inhibition and Medicinal Chemistry;2021-12-11

4. Discovery and optimization of a novel CNS penetrant series of mGlu4 PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model;Bioorganic & Medicinal Chemistry Letters;2021-04

5. Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d2)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain;Journal of Medicinal Chemistry;2020-02-21

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