DFT Study on Retigerane-Type Sesterterpenoid Biosynthesis: Initial Conformation of GFPP Regulates Biosynthetic Pathway, Ring-Construction Order and Stereochemistry

Author:

Watanabe Yuichiro12,Hashishin Takahiro1,Sato Hajime13ORCID,Matsuyama Taro1,Nakajima Masaya1,Haruta Jun-ichi2,Uchiyama Masanobu14ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

2. Graduate School of Pharmaceutical Sciences, Osaka University, Suita-shi, Osaka 565-0871, Japan

3. Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Kofu, Yamanashi 400-8510, Japan

4. Research Initiative for Supra-Materials (RISM), Shinshu University, 3-15-1 Tokida, Ueda, Nagano 386-8567, Japan

Funder

Naito Foundation

Ministry of Education, Culture, Sports, Science and Technology

Inamori Foundation

Core Research for Evolutional Science and Technology

Astellas Foundation for Research on Metabolic Disorders

Precursory Research for Embryonic Science and Technology

Terumo Foundation for Life Sciences and Arts

Japan Society for the Promotion of Science

Nagase Science Technology Foundation

Uehara Memorial Foundation

Chugai Pharmaceutical

Publisher

American Chemical Society (ACS)

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