Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)2malSAHA

Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)2malSAHA–2H)]

Published:2012-05-25 Issue:7 Volume:9 Page:1990-1999
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Brabec Viktor¹,Griffith Darren M.²,Kisova Anna¹,Kostrhunova Hana¹,Zerzankova Lenka¹,Marmion Celine J.²,Kasparkova Jana¹

Affiliation:

1. Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Kralovopolska 135, 61265 Brno, Czech Republic

2. Centre for Synthesis and Chemical Biology, Department of Pharmaceutical & Medicinal Chemistry, Royal College of Surgeons in Ireland, 123 St. Stephen’s Green, Dublin 2, Ireland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp300038f

Reference50 articles.

1. The resurgence of platinum-based cancer chemotherapy

2. What Is the “Best” Platinum: Cisplatin, Carboplatin, or Oxaliplatin?

3. The Discovery and Development of Cisplatin

4. Update of the Preclinical Situation of Anticancer Platinum Complexes: Novel Design Strategies and Innovative Analytical Approaches

5. Biochemical Mechanisms of Cisplatin Cytotoxicity

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Masking the Bioactivity of Hydroxamic Acids by Coordination to Cobalt: Towards Bioreductive Anticancer Agents;Chemistry – A European Journal;2024-07-26

2. Therapeutic regulation of epigenetics in cancer treatment through drug delivery systems;Nano Today;2024-06

3. Advances in the Delivery and Development of Epigenetic Therapeutics for the Treatment of Cancer;Molecular Pharmaceutics;2023-10-30

4. Effect of the hydroxamate group in the antitumoral activity and toxicity toward normal cells of new copper(II) complexes;BioMetals;2021-02-09

5. Pt(IV) pro-drugs with an axial HDAC inhibitor demonstrate multimodal mechanisms involving DNA damage and apoptosis independent of cisplatin resistance in A2780/A2780cis cells;Journal of Inorganic Biochemistry;2020-09