Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists-Reference-Cited by-同舟云学术

Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

Published:2001-05-23 Issue:13 Volume:44 Page:2061-2064
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brooks Dawn A.¹,Etgen Garret J.¹,Rito Christopher J.¹,Shuker Anthony J.¹,Dominianni Samuel J.¹,Warshawsky Alan M.¹,Ardecky Robert¹,Paterniti James R.¹,Tyhonas John¹,Karanewsky Donald S.¹,Kauffman Raymond F.¹,Broderick Carol L.¹,Oldham Brian A.¹,Montrose-Rafizadeh Chahzrad¹,Winneroski Leonard L.¹,Faul Margaret M.¹,McCarthy James R.¹

Affiliation:

1. Lilly Research Laboratories, A Division of Eli Lilly & Company, Lilly Corporate Center, Indianapolis, Indiana 46285, Ligand Pharmaceuticals, 10275 Science Center Drive, San Diego, California 92121

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0155188

Reference23 articles.

1. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

2. The PPARs: From Orphan Receptors to Drug Discovery

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