A Delineation of Diketopiperazine Self-Assembly Processes: Understanding the Molecular Events Involved in Nϵ-(Fumaroyl)diketopiperazine of l-Lys (FDKP) Interactions

Author:

Kaur Navneet1,Zhou Bo1,Breitbeil Fred1,Hardy Katherine1,Kraft Kelly S.1,Trantcheva Iva1,Phanstiel IV Otto1

Affiliation:

1. MannKind Corporation, 1 Casper Street, Danbury, Connecticut 06810, and Department of Chemistry, P.O. Box 162366, University of Central Florida, Orlando, Florida 32816-2366

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference24 articles.

1. aSteiner, S. S.; Rhodes, C. A.; Shen, G.; McCabe, R. T.Method for making self-assembling diketopiperazine drug delivery system. U.S. Patent 5,503,852, April 2,1996.

2. bSteiner,S. S.; Feldstein, R.; Lian, H.; Rhodes, C. A., Shen, G. S.Microparticles for lung delivery comprising diketopiperazine. U.S. Patent 6,071,497, June 6,2000.

3. cPoole, T.; Steiner, S. S.Inhalation apparatus. U.S. Patent 7,140,365, November 28,2006.

4. Macromolecular Self-Assembly of Diketopiperazine Tetrapeptides

5. Influence of structure on the kinetics of assembly of cyclic dipeptides into supramolecular tapes

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