Design, Synthesis, and In Vitro Evaluation of Potential West Nile Virus Protease Inhibitors Based on the 1-Oxo-1,2,3,4-tetrahydroisoquinoline and 1-Oxo-1,2-dihydroisoquinoline Scaffolds-Reference-Cited by-同舟云学术

Design, Synthesis, and In Vitro Evaluation of Potential West Nile Virus Protease Inhibitors Based on the 1-Oxo-1,2,3,4-tetrahydroisoquinoline and 1-Oxo-1,2-dihydroisoquinoline Scaffolds

Published:2010-09-30 Issue:6 Volume:12 Page:836-843
ISSN:1520-4766
Container-title:Journal of Combinatorial Chemistry
language:en
Short-container-title:J. Comb. Chem.

Author:

Dou Dengfeng¹,Viwanathan Prasanth¹,Li Yi¹,He Guijia¹,Alliston Kevin R.¹,Lushington Gerald H.¹,Brown-Clay Joshua D.¹,Padmanabhan R.¹,Groutas William C.¹

Affiliation:

1. Department of Chemistry, Wichita State University, Wichita, Kansas 67260, Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, D.C. 20057, and Molecular Graphics and Modeling Laboratory, The University of Kansas, Lawrence, Kansas 66045

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cc100091h

Reference44 articles.

1. Protease Inhibitors in the Clinic

2. Combinatorial Strategies for Targeting Protein Families: Application to the Proteases

3. Insights to Substrate Binding and Processing by West Nile Virus NS3 Protease through Combined Modeling, Protease Mutagenesis, and Kinetic Studies

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones;PLOS ONE;2023-11-30

2. Cobalt-Catalyzed Enantioselective C–H Annulation with Alkenes;ACS Catalysis;2023-03-13

3. Design and Synthesis of Tetrahydroisoquinoline Derivatives as Anti-Angiogenesis and Anti-Cancer Agents;Anti-Cancer Agents in Medicinal Chemistry;2021-12-23

4. Targeting the protease of West Nile virus;RSC Medicinal Chemistry;2021

5. N-Chloroformylimidazolidinone Enolates as 1,3-Dipolar Reagents for the Stereoselective Synthesis of 3,4-Dihydroisoquinolones;Organic Letters;2019-02-25