Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives-Reference-Cited by-同舟云学术

Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives

Published:2003-11-08 Issue:26 Volume:46 Page:5638-5650
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

López-Rodríguez María L.¹,Porras Esther¹,Morcillo M. José¹,Benhamú Bellinda¹,Soto Luis J.¹,Lavandera José L.¹,Ramos José A.¹,Olivella Mireia¹,Campillo Mercedes¹,Pardo Leonardo¹

Affiliation:

1. Departamento de Química Orgánica I, Facultad de Ciencias Químicas, and Departamento de Bioquímica y Biología Molecular III, Facultad de Medicina, Universidad Complutense, E-28040 Madrid, Spain, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, E-28040 Madrid, Spain, and Laboratori de Medicina Computacional, Unitat de Bioestadística and Institut de Neurociències, Universitat Autònoma de Barcelona, E-08193 Cerdanyola del Vallès, Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030841r

Reference83 articles.

1. A review of central 5-HT receptors and their function

2. Molecular, pharmacological and functional diversity of 5-HT receptors

3. G-Protein Coupled Receptors: Models, Mutagenesis, and Drug Design

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