Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model

Author:

Paterni Ilaria1,Bertini Simone1,Granchi Carlotta1,Tuccinardi Tiziano1,Macchia Marco1,Martinelli Adriano1,Caligiuri Isabella2,Toffoli Giuseppe2,Rizzolio Flavio2,Carlson Kathryn E.3,Katzenellenbogen Benita S.4,Katzenellenbogen John A.3,Minutolo Filippo1

Affiliation:

1. Dipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy

2. Division of Experimental and Clinical Pharmacology, Department of Molecular Biology and Translational Research, CRO National Cancer Institute and Center for Molecular Biomedicine, IRCCS, 33081 Aviano, Pordenone, Italy

3. Department of Chemistry, University of Illinois, 600 S. Mathews Avenue, Urbana, Illinois 61801, United States

4. Department of Molecular and Integrative Physiology, University of Illinois, 407 S. Goodwin Avenue, Urbana, Illinois 61801, United States

Funder

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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