Structure−Activity Relationships Studies in a Series of N,N-Bis(alkanol)amine Aryl Esters as P-Glycoprotein (Pgp) Dependent Multidrug Resistance (MDR) Inhibitors-Reference-Cited by-同舟云学术

Structure−Activity Relationships Studies in a Series of N,N-Bis(alkanol)amine Aryl Esters as P-Glycoprotein (Pgp) Dependent Multidrug Resistance (MDR) Inhibitors

Published:2010-01-27 Issue:4 Volume:53 Page:1755-1762
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Martelli Cecilia¹,Coronnello Marcella²,Dei Silvia¹,Manetti Dina¹,Orlandi Francesca¹,Scapecchi Serena¹,Novella Romanelli Maria¹,Salerno Milena³,Mini Enrico²,Teodori Elisabetta¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Laboratorio di Progettazione Sintesi e Studio di Eterocicli Bioattivi (HeteroBioLab), Università di Firenze, via Ugo Schiff 6, 50019 Sesto Fiorentino (FI), Italy

2. Dipartimento di Farmacologia Preclinica e Clinica, Università di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy

3. Laboratoire de Biophysique Moléculaire, Cellulaire et Tissulaire (BioMoCeTi), UMR CNRS 7033, UMPC Université Paris 6 and Universitè Paris 13, 74 rue Marcel Cachin, 93017 Bobigny, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9016174

Reference50 articles.

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4. Multiple physiological functions for multidrug transporter P-glycoprotein?

5. Multiple drug resistance

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