1,2-Dihydro-4-quinazolinamines: Potent, Highly Selective Inhibitors of Inducible Nitric Oxide Synthase Which Show Antiinflammatory Activity in Vivo-Reference-Cited by-同舟云学术

1,2-Dihydro-4-quinazolinamines: Potent, Highly Selective Inhibitors of Inducible Nitric Oxide Synthase Which Show Antiinflammatory Activity in Vivo

Published:2003-02-07 Issue:6 Volume:46 Page:913-916
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tinker Alan C.¹,Beaton Haydn G.¹,Boughton-Smith Nigel¹,Tony R. Cook, ¹,Cooper Sally L.¹,Fraser-Rae Lynne¹,Hallam Kay¹,Hamley Peter¹,McInally Tom¹,Nicholls David J.¹,Pimm Austen D.¹,Wallace Alan V.¹

Affiliation:

1. Departments of Medicinal Chemistry and BioScience, AstraZeneca R & D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, UK

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0255926

Reference21 articles.

1. Insights into the role of nitric oxide in inflammatory arthritis

2. Inactivation of macrophage nitric oxide synthase activity by NG-Methyl-L-arginine

3. Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine

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