Simultaneous Screen for Microsomal Stability and Metabolite Profile by Direct Injection Turbulent-Laminar Flow LC−LC and Automated Tandem Mass Spectrometry-Reference-Cited by-同舟云学术

Simultaneous Screen for Microsomal Stability and Metabolite Profile by Direct Injection Turbulent-Laminar Flow LC−LC and Automated Tandem Mass Spectrometry

Published:2001-03-30 Issue:9 Volume:73 Page:2140-2146
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Lim H. K.¹,Chan K. W.¹,Sisenwine S.¹,Scatina J. A.¹

Affiliation:

1. Drug Safety and Metabolism, Wyeth-Ayerst Research, 9 DeerPark Drive, Building 3, Monmouth Junction, New Jersey 08852

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac001112b

Reference15 articles.

1. Role of the Development Scientist in Compound Lead Selection and Optimization

2. High throughput liquid chromatography/mass spectrometry bioanalysis using 96-well disk solid phase extraction plate for the sample preparation

3. The use of turbulent flow chromatography/mass spectrometry for the rapid, direct analysis of a novel pharmaceutical compound in plasma

4. Korfmacher, W. A.; Bryant, M. S.; Cox, K. A.; Ng, K. K.; Veals, J.; Clarke, N.; Hsieh, Y. S.; Palmer, C. A.; Lin, C. C. Proceedings of the 47th ASMS Conference on Mass Spectrometry and Allied Topics, Dallas, TX, 1999; p 1135.

5. Direct plasma injection for high-performance liquid chromatographic–mass spectrometric quantitation of the anxiolytic agent CP-93 393

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