Gene and Protein Expression of P-Glycoprotein, MRP1, MRP2, and CYP3A4 in the Small and Large Human Intestine-Reference-Cited by-同舟云学术

Gene and Protein Expression of P-Glycoprotein, MRP1, MRP2, and CYP3A4 in the Small and Large Human Intestine

Published:2007-01-31 Issue:2 Volume:4 Page:252-257
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Berggren Sofia¹,Gall Christine¹,Wollnitz Nadine¹,Ekelund Mats¹,Karlbom Urban¹,Hoogstraate Janet¹,Schrenk Dieter¹,Lennernäs Hans¹

Affiliation:

1. Department of Pharmacy, Uppsala University, Uppsala, Sweden, Food Chemistry and Environmental Toxicology, University of Kaiserslautern, Kaiserslautern, Germany, Department of Clinical Sciences Lund, Division of Surgery, Lund University, Lund, Sweden, Surgical Sciences, Division of Surgery, Uppsala University, Sweden, and Research DMPK, AstraZeneca R&D, Södertälje, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp0600687

Reference31 articles.

1. Role of P-Glycoprotein and Cytochrome P450 3A in Limiting Oral Absorption of Peptides and Peptidomimetics†

2. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

3. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

4. Direct demonstration of small intestinal secretion and site-dependent absorption of the β-blocker talinolol in humans*

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