1. Department of Food and Nutrition, Research Institute of Biotechnology, Hungkuang University, 34 Chung-Chie Road, Shalu County, Taichung Hsien, Taiwan 43302; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chung-Shan Medical University Hospital, Chung-Shan Medical University, 110 Chien-Kuo S. Road, Taichung City, Taiwan; and Research Institute of Medical Sciences, Taipei Medical University, Wu-Xin Street, Xin-Yi District, Taipei 110, Taiwan