Highly Potent and Selective Ectonucleotide Pyrophosphatase/Phosphodiesterase I Inhibitors Based on an Adenosine 5′-(α or γ)-Thio-(α,β- or β,γ)-methylenetriphosphate Scaffold-Reference-Cited by-同舟云学术

Highly Potent and Selective Ectonucleotide Pyrophosphatase/Phosphodiesterase I Inhibitors Based on an Adenosine 5′-(α or γ)-Thio-(α,β- or β,γ)-methylenetriphosphate Scaffold

Published:2014-05-30 Issue:11 Volume:57 Page:4677-4691
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nadel Yael¹,Lecka Joanna²³,Gilad Yocheved¹,Ben-David Gal¹,Förster Daniel⁴,Reiser Georg⁴,Kenigsberg Sarah¹,Camden Jean⁵,Weisman Gary A.⁵,Senderowitz Hanoch¹,Sévigny Jean²³,Fischer Bilha¹

Affiliation:

1. Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel

2. Département de microbiologie-infectiologie et d’immunologie, Faculté de Médecine, Université Laval, Québec, Québec G1V 0A6, Canada

3. Centre de recherche du CHU de Québec, Québec, Québec G1V 4G2, Canada

4. Otto von Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany

5. Biochemistry Department, University of Missouri—Columbia, 540E Bond Life Sciences Center, Columbia, Missouri 65211, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500196c