1. Division of Pulmonary/Critical Care Medicine, Department of Internal Medicine, University of Cincinnati, 231 Bethesda Avenue, Cincinnati, Ohio 45267-0564, Department of Molecular Biology and Genetics, University of Guelph, Guelph, Ontario, Canada N1G 2W1, and Medical Research Council Group in Fetal and Neonatal Health and Development, Departments of Obstetrics and Gynecology and Biochemistry, University of Western Ontario, London, Ontario, Canada N6A 5A5