Synthesis and Biological Evaluation of 6-(Alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one Base and Nucleoside Derivatives-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 6-(Alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one Base and Nucleoside Derivatives

Published:2005-11-30 Issue:1 Volume:49 Page:391-398
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Robins Morris J.¹,Miranda Karl¹,Rajwanshi Vivek K.¹,Peterson Matt A.¹,Andrei Graciela¹,Snoeck Robert¹,De Clercq Erik¹,Balzarini Jan¹

Affiliation:

1. Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602-5700, and Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050867d

Reference14 articles.

1. Nucleic acid related compounds. 31. Smooth and efficient palladium-copper catalyzed coupling of terminal alkynes with 5-iodouracil nucleosides

2. Nucleic acid related compounds. 39. Efficient conversion of 5-iodo to 5-alkynyl and derived 5-substituted uracil bases and nucleosides

3. Nucleic acid related compounds. 40. Synthesis and biological activities of 5-alkynyluracil nucleosides

4. Potent and Selective Inhibition of Varicella-Zoster Virus (VZV) by Nucleoside Analogues with an Unusual Bicyclic Base

5. Highly Potent and Selective Inhibition of Varicella-Zoster Virus by Bicyclic Furopyrimidine Nucleosides Bearing an Aryl Side Chain

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