1. Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2 Universitetsparken, DK-2100 Copenhagen, Denmark, Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, Atlanta, Georgia, Department of Medicinal Chemistry and Department of Molecular Neurobiology, H. Lundbeck A/S, 9 Ottiliavej, DK-2500 Valby, Denmark