Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics
Author:
Affiliation:
1. Cylene Pharmaceuticals, 5820 Nancy Ridge Drive, Suite 200, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml300110s
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1. Non-Oncogene Addiction and the Stress Phenotype of Cancer Cells
2. Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
3. Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus
4. At the crossroads of growth control; making ribosomal RNA
5. The RNA polymerase I transcription machinery
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