1. Department of Pharmaceutical and Biological Chemistry, School of Pharmacy, 29-39 Brunswick Square, University of London, London WC1N 1AX, U.K, Department of Pharmacy, De Montfort University, Leicester LE1 9BH, U.K., Cancer Research U.K., Drug−DNA Interactions Research Group, Department of Oncology, UCL, London W1W 7BS, U.K., and Cancer Research U.K., Centre for Cancer Therapeutics, The Institute of Cancer Research, Sutton, SM2 5NG, Surrey, UK