Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann−Pick Type C Disease Therapeutics
Author:
Affiliation:
1. Department of Biochemistry, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10065
2. Department of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, Indiana 46556
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm100499s
Reference35 articles.
1. The pathophysiology and mechanisms of NP-C disease
2. Lipid and cholesterol trafficking in NPC
3. Role of cholesterol and lipid organization in disease
4. Neuronal Protein Trafficking in Alzheimer's Disease and Niemann-Pick Type C Disease
5. The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts.
Cited by 81 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death;Cell Reports;2024-07
2. DFCP1 is a Regulator of ATGL-mediated Lipid Droplet Lipolysis;2024-02-15
3. Electrochemical Synthesis of 3,5-Bis(acyl)-1,2,4-thiadiazoles through <i>n</i>-Bu<sub>4</sub>NI-mediated Oxidative Dimerization of α-Oxothioamides;Electrochemistry;2023-12-28
4. Orthodenticle homeobox 2 is transported to lysosomes by nuclear budding vesicles;Nature Communications;2023-02-27
5. Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development;Nature Communications;2022-07-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3