Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP)-Reference-Cited by-同舟云学术

Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP)

Published:2008-10-28 Issue:22 Volume:51 Page:7169-7180
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sun Haiying¹,Stuckey Jeanne A.¹,Nikolovska-Coleska Zaneta¹,Qin Dongguang¹,Meagher Jennifer L.¹,Qiu Su¹,Lu Jianfeng¹,Yang Chao-Yie¹,Saito Naoyuki G.¹,Wang Shaomeng¹

Affiliation:

1. Departments of Internal Medicine, Biological Chemistry, Pharmacology, Medicinal Chemistry, Radiation Oncology, Comprehensive Cancer Center, Life Sciences Institute, Biophysics Research Division, University of Michigan, Ann Arbor, Michigan 48109

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8006849

Reference46 articles.

1. Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

2. Apoptosis in the Pathogenesis and Treatment of Disease

3. From bench to clinic with apoptosis-based therapeutic agents

4. Apoptosis-based therapies

5. IAP family proteins---suppressors of apoptosis

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