Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors

Author:

Kumar Sanjeev1,Malachowski William P.1,DuHadaway James B.1,LaLonde Judith M.1,Carroll Patrick J.1,Jaller Daniel1,Metz Richard1,Prendergast George C.1,Muller Alexander J.1

Affiliation:

1. Department of Chemistry, Bryn Mawr College, Bryn Mawr, Pennsylvania 19010, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, Department of Chemistry, X-ray Crystallography Facility, University of Pennsylvania, Philadelphia, Pennsylvania 19104, LIMR Development, Inc., Wynnewood, Pennsylvania 19096, and Departments of Pathology, Anatomy & Cell Biology, Microbiology and Immunology, Jefferson Medical School, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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