Inhibitors of Trypanosoma cruzi Trypanothione Reductase Revealed by Virtual Screening and Parallel Synthesis-Reference-Cited by-同舟云学术

Inhibitors of Trypanosoma cruzi Trypanothione Reductase Revealed by Virtual Screening and Parallel Synthesis

Published:2005-06-25 Issue:15 Volume:48 Page:4793-4802
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Meiering Svea¹,Inhoff Oliver¹,Mies Jan¹,Vincek Adam¹,Garcia Gabriel¹,Kramer Bernd¹,Dormeyer Matthias¹,Krauth-Siegel R. Luise¹

Affiliation:

1. Biochemie-Zentrum, Universität Heidelberg, Im Neuenheimer Feld 504, D-69120 Heidelberg, Germany, and 4SC AG, Am Klopferspitz 19a, D-82152 Martinsried, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050027z

Reference49 articles.

1. METABOLISM AND FUNCTIONS OF TRYPANOTHIONE IN THE KINETOPLASTIDA

2. Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in Trypanosomatids

3. Evidence for the co-existence of glutathione reductase and trypanothione reductase in the non-trypanosomatid Euglenozoa: Euglena gracilis Z

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