Chemistry-Based Risk Assessment for Skin Sensitization: Quantitative Mechanistic Modeling for the SNAr Domain-Reference-Cited by-同舟云学术

Chemistry-Based Risk Assessment for Skin Sensitization: Quantitative Mechanistic Modeling for the SNAr Domain

Published:2011-06-23 Issue:7 Volume:24 Page:1003-1011
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Roberts D. W.¹,Aptula A. O.²,Patlewicz G. Y.³

Affiliation:

1. School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, England

2. SEAC, Unilever Colworth, Sharnbrook, Bedford MK44 1LQ, England

3. DuPont Haskell Global Centers for Health and Environmental Sciences, Newark, Delaware 19711, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx100420w

Reference51 articles.

1. Local lymph node assay: use in hazard and risk assessment

2. The Local Lymph Node Assay: Current Position in the Regulatory Classification of Skin Sensitizing Chemicals

3. OECD (2002) Guidelines for Testing of Chemicals, Guideline No. 429, Skin Sensitization: The Local Lymph Node Assay, Organisation for Economic Cooperation and Development, Paris, France.

4. The derivation of quantitative correlations between skin sensitisation and physio-chemical parameters for alkylating agents, and their application to experimental data for sultones

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