Structure–Activity Relationship Studies of Indole-Based Compounds as Small Molecule HIV-1 Fusion Inhibitors Targeting Glycoprotein 41-Reference-Cited by-同舟云学术

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Structure–Activity Relationship Studies of Indole-Based Compounds as Small Molecule HIV-1 Fusion Inhibitors Targeting Glycoprotein 41

Published:2014-06-06 Issue:12 Volume:57 Page:5270-5281
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Guangyan¹,Sofiyev Vladimir¹,Kaur Hardeep¹,Snyder Beth A.²,Mankowski Marie K.²,Hogan Priscilla A.²,Ptak Roger G.²,Gochin Miriam¹³

Affiliation:

1. Department of Basic Sciences, Touro University—California, 1310 Club Drive, Mare Island, Vallejo, California 94592, United States

2. Southern Research Institute, 431 Aviation Way, Frederick, Maryland 21701, United States

3. Department of Pharmaceutical Chemistry, University of California—San Francisco, San Francisco, California 94143, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500344y

Reference57 articles.

1. Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion

2. HIV-1 Membrane Fusion

3. HIV-1 gp41 Six-Helix Bundle Formation Occurs Rapidly after the Engagement of gp120 by CXCR4 in the HIV-1 Env-Mediated Fusion Process

4. Kinetic Dependence to HIV-1 Entry Inhibition

5. Mechanisms of Viral Membrane Fusion and Its Inhibition

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1. Multi-hydroxyl POSS supported iridium complexes as a recyclable catalyst for selective synthesis of N-/C-substituted indoles and the total synthesis of HIV-1 fusion inhibitor;Journal of Catalysis;2024-01

2. Multi-Hydroxyl POSS Supported Iridium Complexes as a Recyclable Catalyst for Selective Synthesis of N-/C-Substituted Indoles and the Total Synthesis of HIV-1 Fusion Inhibitor;2023

3. Targeting a Conserved Lysine in the Hydrophobic Pocket of HIV-1 gp41 Improves Small Molecule Antiviral Activity;Viruses;2022-12-02

4. Novel 2-alkylthio-1-benzylimidazole-5-carboxylic Acid Derivatives Targeting Gp41: Design, Synthesis, and In Vitro Anti-HIV Activity Evaluation;Current HIV Research;2022-09

5. Therapeutic potential of indole derivatives as anti-HIV agents: A mini-review;Current Topics in Medicinal Chemistry;2021-10-12

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