Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors-Reference-Cited by-同舟云学术

Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors

Published:2013-11-08 Issue:1 Volume:9 Page:301-309
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Schorn Michelle¹,Zettler Judith²³,Noel Joseph P.⁴,Dorrestein Pieter C.⁵,Moore Bradley S.¹⁵,Kaysser Leonard¹²³

Affiliation:

1. Scripps Institution of Oceanography, University of California, San Diego, California 92093, United States of America

2. Pharmaceutical Biology, Eberhard Karls University Tübingen, 72076 Tübingen, Germany

3. German Center for Infection Research (DZIF), partner site Tübingen, 72076 Tübingen, Germany

4. Jack H. Skirball Center for Chemical Biology and Proteomics, Salk Institute for Biological Studies, La Jolla, California 92037, United States of America

5. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California 92093, United States of America

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb400699p

Reference50 articles.

1. The ubiquitin-proteasome proteolytic pathway

2. p53-dependent Induction of Apoptosis by Proteasome Inhibitors

3. Activation of the cell death program by inhibition of proteasome function

4. Exploiting nature's rich source of proteasome inhibitors as starting points in drug development

5. Epoxomicin, a new antitumor agent of microbial origin.

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