pH-Responsive Multifunctional Theranostic Rapamycin-Loaded Nanoparticles for Imaging and Treatment of Acute Ischemic Stroke

Author:

Cheng Yan1ORCID,Cheng Airong2,Jia Yanlong3,Yang Lin1,Ning Yan4,Xu Liang1,Zhong Yazhi1,Zhuang Zerui567,Guan Jitian1ORCID,Zhang Xiaolei1,Lin Yan1,Zhou Teng8,Fan Xiusong9,Li Jianwu10,Liu Peng11,Yan Gen12,Wu Renhua1

Affiliation:

1. Department of Radiology, The Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, Guangdong, China

2. Department of Neurology, Chengwu County People’s Hospital, Chengwu 274200, Shandong, China

3. Department of Radiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei 441021, China

4. Department of TCM, Shenzhen Maternity & Child Healthcare Hospital Affiliated to Southern Medical University, Shenzhen 518028, Guangdong, China

5. Department of Neurosurgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China

6. Department of Neurosurgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-Sen University, Shantou 515041, Guangdong, China

7. Department of Neurosurgery, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, Guangdong, China

8. Department of Computer Science, Shantou University, Shantou 515041, China

9. Department of Radiology, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong, China

10. Transfusion Department, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong, China

11. National & Local Joint Engineering Research Center of Orthopaedic Biomaterials, Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong, China

12. Department of Radiology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen 361023, Fujian, China

Funder

National Natural Science Foundation of China

Guangdong High-Level University Development Program

2020 Li Ka Shing Foundation Cross-Disciplinary Research

2020 LKSF Cross-Disciplinary Research

Shenzhen Science and Technology Program

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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