Indazole- and Indole-5-carboxamides: Selective and Reversible Monoamine Oxidase B Inhibitors with Subnanomolar Potency
Author:
Affiliation:
1. Pharmaceutical Institute, Pharmaceutical Chemistry I, PharmaCenter Bonn, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany
2. BioSolveIT GmbH, An der Ziegelei 79, 53757 St. Augustin, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm500729a
Reference109 articles.
1. Monoamine oxidase B inhibition and neuroprotection: Studies on selective adenosine A2A receptor antagonists
2. MONOAMINE OXIDASE: From Genes to Behavior
3. Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders
4. Structural Comparison of Human Monoamine Oxidases A and B
5. Selective MAO-A and B inhibitors, radical scavengers and nitric oxide synthase inhibitors in Parkinson's desease
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