PockDrug: A Model for Predicting Pocket Druggability That Overcomes Pocket Estimation Uncertainties
Author:
Affiliation:
1. INSERM, UMRS-973, MTi, Paris, France
2. University Paris Diderot, Sorbonne Paris Cité, UMRS-973, MTi, Paris, France
3. University of Helsinki, Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Helsinki, Finland
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci5006004
Reference43 articles.
1. The druggable genome
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3. Cofactor-Independent Phosphoglycerate Mutase from Nematodes Has Limited Druggability, as Revealed by Two High-Throughput Screens
4. Druggability Indices for Protein Targets Derived from NMR-Based Screening Data
5. Structure-based maximal affinity model predicts small-molecule druggability
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