Electrophilic Chemistry Related to Skin Sensitization. Reaction Mechanistic Applicability Domain Classification for a Published Data Set of 106 Chemicals Tested in the Mouse Local Lymph Node Assay-Reference-Cited by-同舟云学术

Electrophilic Chemistry Related to Skin Sensitization. Reaction Mechanistic Applicability Domain Classification for a Published Data Set of 106 Chemicals Tested in the Mouse Local Lymph Node Assay

Published:2006-12-13 Issue:1 Volume:20 Page:44-60
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Roberts David W.¹,Aptula Aynur O.¹,Patlewicz Grace¹

Affiliation:

1. School of Pharmacy and Chemistry, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, England, SEAC, Unilever Colworth, Sharnbrook, Bedford MK44 1LQ, England, and European Chemicals Bureau TP582, Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Via Fermi, 21020 Ispra (VA), Italy

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx060121y

Reference58 articles.

1. The murine local lymph node assay: A commentary on collaborative studies and new directions

2. The derivation of quantitative correlations between skin sensitisation and physio-chemical parameters for alkylating agents, and their application to experimental data for sultones

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