1. Group of Bioinformatics, Vavilov Institute of General Genetics, RAS, Gubkina 3, Moscow 119991, Russia, Institute of Bioinformatics, GSF-National Research Center for Environment and Health, Ingostaedter Landstr.1, Neuherberg 85764, Germany, Institute for Information Transmission Problems, RAS, Bolshoi Karetny pereulok 19, Moscow 127994, Russia, and Faculty of Bioengineering and Bioinformatics, Moscow State University, Vorobievy Gory 1-73, Moscow 119992, Russia