Amino Acid Substitution in the Active Site of DNA Polymerase β Explains the Energy Barrier of the Nucleotidyl Transfer Reaction-Reference-Cited by-同舟云学术

Amino Acid Substitution in the Active Site of DNA Polymerase β Explains the Energy Barrier of the Nucleotidyl Transfer Reaction

Published:2013-05-16 Issue:21 Volume:135 Page:8078-8088
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Batra Vinod K.¹,Perera Lalith¹,Lin Ping²,Shock David D.¹,Beard William A.¹,Pedersen Lars C.¹,Pedersen Lee G.¹³,Wilson Samuel H.¹

Affiliation:

1. Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, P.O. Box 12233, Research Triangle Park, North Carolina 27709-12233, United States

2. Penn State University, 320 Steidle PSU, University Park, Pennsylvania 16802, United States

3. Department of Chemistry, CB3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja403842j

Reference35 articles.

1. DNA polymerase POLQ and cellular defense against DNA damage

2. Eukaryotic DNA Polymerases

3. DNA polymerases and cancer

4. DNA Replication Fidelity

5. Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

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