Diastereoselective Reaction of a Grignard Reagent with Chiral Imides:  A Practical Preparation of a Key Intermediate in the Synthesis of Ifetroban Sodium

Author:

Mueller Richard H.1,Wang Shaopeng1,Pansegrau Paul D.1,Jannotti Joy Q.1,Poss Michael A.1,Thottathil John K.1,Singh Janak1,Humora Michael J.1,Kissick Thomas P.1,Boyhan Brenda1

Affiliation:

1. Chemical Process Research Department, The Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543-4000, and P.O. Box 191, New Brunswick, New Jersey 08903-0191

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

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