Molecular Models of N-Benzyladriamycin-14-valerate (AD 198) in Complex with the Phorbol Ester-Binding C1b Domain of Protein Kinase C-δ-Reference-Cited by-同舟云学术

Molecular Models of N-Benzyladriamycin-14-valerate (AD 198) in Complex with the Phorbol Ester-Binding C1b Domain of Protein Kinase C-δ

Published:2001-03-01 Issue:7 Volume:44 Page:1028-1034
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Roaten J. Brent¹,Kazanietz Marcelo G.¹,Sweatman Trevor W.¹,Lothstein Leonard¹,Israel Mervyn¹,Parrill Abby L.¹

Affiliation:

1. Department of Pharmacology, University of Tennessee College of Medicine, Memphis, Tennessee 38163, Department of Pharmacology and Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6160, and Department of Chemistry, Computational Research on Materials Institute, University of Memphis, Memphis, Tennessee 38152-6060

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000289v

Reference39 articles.

1. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

2. Sweatman, T. W.; Israel, M. InAnthracyclines; Teicher, B. A., Ed.; Humana Press Inc. Totowa, NJ, 1997; p 451.

3. Amelioration of adriamycin toxicity through modification of drug-DNA binding properties

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pivarubicin Is More Effective Than Doxorubicin Against Triple-Negative Breast Cancer In Vivo;Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics;2020-12-10

2. C1 Domains: Structure and Ligand-Binding Properties;Chemical Reviews;2014-11-06

3. N-benzyladriamycin-14-valerate (AD 198) exhibits potent anti-tumor activity on TRAF3-deficient mouse B lymphoma and human multiple myeloma;BMC Cancer;2013-10-16

4. Current Status and Future Prospects of C1 Domain Ligands as Drug Candidates;Current Topics in Medicinal Chemistry;2011-06-01

5. Protection from Doxorubicin-Induced Cardiomyopathy Using the Modified Anthracycline N-Benzyladriamycin-14-valerate (AD 198);Journal of Pharmacology and Experimental Therapeutics;2010-07-28