1. Graduate Institute of Bioindustrial Technology, Da-Yeh University, 112, Shan-Jiao Road, Dah-Tsuen, Changhua County, Taiwan 515, Department of Food and Nutrition and Research Institute of Biotechnology, Hungkuang University, 34, Chung-Chie Road, Sha-Lu County, Taichung Hsien, Taiwan 43302, and Research Institute of Medical Sciences, Taipei Medical University, 252, Wu-Xin Street, Xin-Yi District, Taipei 116