4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]- phenol Hydrochloride (SIB-1553A): A Novel Cognitive Enhancer with Selectivity for Neuronal Nicotinic Acetylcholine Receptors-Reference-Cited by-同舟云学术

4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]- phenol Hydrochloride (SIB-1553A): A Novel Cognitive Enhancer with Selectivity for Neuronal Nicotinic Acetylcholine Receptors

Published:1999-04-30 Issue:10 Volume:42 Page:1684-1686
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vernier Jean-Michel¹,El-Abdellaoui Hassan¹,Holsenback Heather¹,Cosford Nicholas D. P.¹,Bleicher Leo¹,Barker Geoffrey¹,Bontempi Bruno¹,Chavez-Noriega Laura¹,Menzaghi Frederique¹,Rao Tadimeti S.¹,Reid Richard¹,Sacaan Aida I.¹,Suto Carla¹,Washburn Mark¹,Lloyd G. Kenneth¹,McDonald Ian A.¹

Affiliation:

1. SIBIA Neurosciences Inc., 505 Coast Boulevard South, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990035d

Reference29 articles.

1. Characterization of l-[3H]Nicotine Binding in Human Cerebral Cortex: Comparison Between Alzheimer's Disease and the Normal

2. Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains

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